Furosemide sodium

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Furosemide sodium 是 Na+/K+/2Cl-?(NKCC)，NKCC1 和 NKCC2 共转运蛋白的有效的和具有口服活性抑制剂。Furosemide sodium 也是 GABAA 受体拮抗剂，对含 α6 受体的选择性是含 α1 受体的 100 倍。Furosemide sodium 用作利尿试剂，用于充血性心力衰竭，高血压和水肿的研究。

Furosemide sodium is a potent and orally active inhibitor of Na+/K+/2Cl-?(NKCC) cotransporter, NKCC1 and NKCC2.?Furosemide sodium is also a GABAA?receptors antagonist and displays 100-fold selectivity for?α6-containing receptors than?α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema.

——

——

——

Others

Other Targets

GABA Receptor | Na-K-Cl cotransporter

——

——

41733-55-5

352.73

C12H10ClN2NaO5S

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : ≥ 150 mg/mL (425.25 mM) H2O 中的溶解度 : 100 mg/mL (283.50 mM; 超声助溶)

O=C([O-])C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC2=CC=CO2.[Na+]

——

(-20℃)

With Ice Pack

≥ 2 years